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1.
Artigo em Inglês | MEDLINE | ID: mdl-25460781

RESUMO

Short Communication selected from the Oral Presentations of the 56th Congress of the Groupèment International pour la Recherche Scientifique en Stomatologie et Odontologie, Peñafiel (Portugal) May 2012.

2.
Rev Argent Microbiol ; 34(3): 117-23, 2002.
Artigo em Espanhol | MEDLINE | ID: mdl-12415893

RESUMO

In the context of HIV infection, cryptococcal meningitis is the most common mycosis threatening the patient's life. We conducted a retrospective evaluation to determine the epidemiological, microbiological, immunological and clinical characteristics of disseminated cryptococcosis in 51 hospitalised HIV seropositive patients. All the individuals (n = 51) presented reactive serology for HIV (ELISA and/or Western blot) and none fulfilled strict HAART treatment, previous to the opportunistic infection. CD4+ lymphocyte T counts showed levels between 361 and 0 cells/microliter (mean = 45). All patients but one had counts lower than 100 cells/microliter. Cryptococcosis presented as unique episode in 35 patients (68.6%) and in 16 as relapse (31.3%). In all of them we detected central nervous system involvement. The induction treatment was carried out with amphotericin B (AMB), continued with maintenance therapy with fluconazole. Lethality rate was 36.7%, slightly superior among patients in relapse (40%) compared to those who presented a first episode of the mycosis (35.2%). In those individuals for whom data were available, 65.2% of blood cultures, 94.1% of CSF cultures and 79.06% of microscopic CSF examination with India ink were positive. Titers of Cryptococcus neoformans capsular antigen in CSF > or = 1/1000 were found in 36.1% and > or = 1/1000 in 73.6% of serum samples. In conclusion, manifestations and severity of disseminated cryptococcosis continue maintaining the characteristics of half a decade behind, in those patients who are not treated with HAART. Neurological involvement existed in all patients of this cohort. Treatment is not able to modify the parameters of mortality seen in previous communications. Diagnostic methods applied in this study are in accordance with those in the bibliography.


Assuntos
Infecções Oportunistas Relacionadas com a AIDS/epidemiologia , Criptococose/epidemiologia , Infecções Oportunistas Relacionadas com a AIDS/imunologia , Infecções Oportunistas Relacionadas com a AIDS/microbiologia , Doença Aguda , Adulto , Anfotericina B/uso terapêutico , Antifúngicos/uso terapêutico , Antígenos de Fungos/sangue , Antígenos de Fungos/líquido cefalorraquidiano , Terapia Antirretroviral de Alta Atividade , Argentina/epidemiologia , Contagem de Linfócito CD4 , Criptococose/tratamento farmacológico , Criptococose/imunologia , Criptococose/microbiologia , Cryptococcus neoformans/imunologia , Cryptococcus neoformans/isolamento & purificação , Fluconazol/uso terapêutico , Anticorpos Anti-HIV/sangue , HIV-1 , Humanos , Pacientes Internados , Masculino , Meningite Criptocócica/líquido cefalorraquidiano , Meningite Criptocócica/tratamento farmacológico , Meningite Criptocócica/epidemiologia , Meningite Criptocócica/imunologia , Meningite Criptocócica/microbiologia , Pessoa de Meia-Idade , Recidiva , Estudos Retrospectivos
3.
Rev. argent. microbiol ; 34(3): 117-123, jul.-sept. 2002.
Artigo em Espanhol | LILACS | ID: lil-331794

RESUMO

In the context of HIV infection, cryptococcal meningitis is the most common mycosis threatening the patient's life. We conducted a retrospective evaluation to determine the epidemiological, microbiological, immunological and clinical characteristics of disseminated cryptococcosis in 51 hospitalised HIV seropositive patients. All the individuals (n = 51) presented reactive serology for HIV (ELISA and/or Western blot) and none fulfilled strict HAART treatment, previous to the opportunistic infection. CD4+ lymphocyte T counts showed levels between 361 and 0 cells/microliter (mean = 45). All patients but one had counts lower than 100 cells/microliter. Cryptococcosis presented as unique episode in 35 patients (68.6) and in 16 as relapse (31.3). In all of them we detected central nervous system involvement. The induction treatment was carried out with amphotericin B (AMB), continued with maintenance therapy with fluconazole. Lethality rate was 36.7, slightly superior among patients in relapse (40) compared to those who presented a first episode of the mycosis (35.2). In those individuals for whom data were available, 65.2 of blood cultures, 94.1 of CSF cultures and 79.06 of microscopic CSF examination with India ink were positive. Titers of Cryptococcus neoformans capsular antigen in CSF > or = 1/1000 were found in 36.1 and > or = 1/1000 in 73.6 of serum samples. In conclusion, manifestations and severity of disseminated cryptococcosis continue maintaining the characteristics of half a decade behind, in those patients who are not treated with HAART. Neurological involvement existed in all patients of this cohort. Treatment is not able to modify the parameters of mortality seen in previous communications. Diagnostic methods applied in this study are in accordance with those in the bibliography.


Assuntos
Humanos , Masculino , Adulto , Pessoa de Meia-Idade , Criptococose , Infecções Oportunistas Relacionadas com a AIDS/epidemiologia , Doença Aguda , Anfotericina B , Antígenos de Fungos/sangue , Antígenos de Fungos/líquido cefalorraquidiano , Antifúngicos/uso terapêutico , Terapia Antirretroviral de Alta Atividade , Argentina , Criptococose , Cryptococcus neoformans , Fluconazol , Anticorpos Anti-HIV , HIV-1 , Infecções Oportunistas Relacionadas com a AIDS/imunologia , Infecções Oportunistas Relacionadas com a AIDS/microbiologia , Pacientes Internados , Meningite Criptocócica/líquido cefalorraquidiano , Meningite Criptocócica/tratamento farmacológico , Meningite Criptocócica/epidemiologia , Meningite Criptocócica/imunologia , Meningite Criptocócica/microbiologia , Recidiva , Estudos Retrospectivos
4.
Rev. argent. microbiol ; 34(3): 117-123, jul.-sept. 2002.
Artigo em Espanhol | BINACIS | ID: bin-6782

RESUMO

In the context of HIV infection, cryptococcal meningitis is the most common mycosis threatening the patients life. We conducted a retrospective evaluation to determine the epidemiological, microbiological, immunological and clinical characteristics of disseminated cryptococcosis in 51 hospitalised HIV seropositive patients. All the individuals (n = 51) presented reactive serology for HIV (ELISA and/or Western blot) and none fulfilled strict HAART treatment, previous to the opportunistic infection. CD4+ lymphocyte T counts showed levels between 361 and 0 cells/microliter (mean = 45). All patients but one had counts lower than 100 cells/microliter. Cryptococcosis presented as unique episode in 35 patients (68.6) and in 16 as relapse (31.3). In all of them we detected central nervous system involvement. The induction treatment was carried out with amphotericin B (AMB), continued with maintenance therapy with fluconazole. Lethality rate was 36.7, slightly superior among patients in relapse (40) compared to those who presented a first episode of the mycosis (35.2). In those individuals for whom data were available, 65.2 of blood cultures, 94.1 of CSF cultures and 79.06 of microscopic CSF examination with India ink were positive. Titers of Cryptococcus neoformans capsular antigen in CSF > or = 1/1000 were found in 36.1 and > or = 1/1000 in 73.6 of serum samples. In conclusion, manifestations and severity of disseminated cryptococcosis continue maintaining the characteristics of half a decade behind, in those patients who are not treated with HAART. Neurological involvement existed in all patients of this cohort. Treatment is not able to modify the parameters of mortality seen in previous communications. Diagnostic methods applied in this study are in accordance with those in the bibliography.(AU)


Assuntos
Humanos , Masculino , Adulto , Pessoa de Meia-Idade , Infecções Oportunistas Relacionadas com a AIDS/epidemiologia , Criptococose/epidemiologia , Infecções Oportunistas Relacionadas com a AIDS/imunologia , Infecções Oportunistas Relacionadas com a AIDS/microbiologia , Doença Aguda , Anfotericina B/uso terapêutico , Antifúngicos/uso terapêutico , Antígenos de Fungos/sangue , Antígenos de Fungos/líquido cefalorraquidiano , Terapia Antirretroviral de Alta Atividade , Argentina/epidemiologia , Contagem de Linfócito CD4 , Criptococose/tratamento farmacológico , Criptococose/imunologia , Criptococose/microbiologia , Cryptococcus neoformans/imunologia , Cryptococcus neoformans/isolamento & purificação , Fluconazol/uso terapêutico , Anticorpos Anti-HIV/sangue , HIV-1 , Pacientes Internados , Meningite Criptocócica/líquido cefalorraquidiano , Meningite Criptocócica/tratamento farmacológico , Meningite Criptocócica/epidemiologia , Meningite Criptocócica/imunologia , Meningite Criptocócica/microbiologia , Recidiva , Estudos Retrospectivos
5.
Rev. argent. microbiol ; 34(3): 117-23, 2002 Jul-Sep.
Artigo em Espanhol | BINACIS | ID: bin-39119

RESUMO

In the context of HIV infection, cryptococcal meningitis is the most common mycosis threatening the patients life. We conducted a retrospective evaluation to determine the epidemiological, microbiological, immunological and clinical characteristics of disseminated cryptococcosis in 51 hospitalised HIV seropositive patients. All the individuals (n = 51) presented reactive serology for HIV (ELISA and/or Western blot) and none fulfilled strict HAART treatment, previous to the opportunistic infection. CD4+ lymphocyte T counts showed levels between 361 and 0 cells/microliter (mean = 45). All patients but one had counts lower than 100 cells/microliter. Cryptococcosis presented as unique episode in 35 patients (68.6


) and in 16 as relapse (31.3


). In all of them we detected central nervous system involvement. The induction treatment was carried out with amphotericin B (AMB), continued with maintenance therapy with fluconazole. Lethality rate was 36.7


, slightly superior among patients in relapse (40


) compared to those who presented a first episode of the mycosis (35.2


). In those individuals for whom data were available, 65.2


of blood cultures, 94.1


of CSF cultures and 79.06


of microscopic CSF examination with India ink were positive. Titers of Cryptococcus neoformans capsular antigen in CSF > or = 1/1000 were found in 36.1


and > or = 1/1000 in 73.6


of serum samples. In conclusion, manifestations and severity of disseminated cryptococcosis continue maintaining the characteristics of half a decade behind, in those patients who are not treated with HAART. Neurological involvement existed in all patients of this cohort. Treatment is not able to modify the parameters of mortality seen in previous communications. Diagnostic methods applied in this study are in accordance with those in the bibliography.

6.
Acta Gastroenterol Latinoam ; 31(5): 399-402, 2001.
Artigo em Espanhol | MEDLINE | ID: mdl-11873668

RESUMO

Strongyloides stercoralis is an intestinal nematode that infects humans worldwide. Infected patients with severe involvement of cellular immunity may develop a syndrome characterized by the dissemination of larvae throughout the body. Extraintestinal strongyloidiasis has been infrequently reported and despite the prevalence of the helminth in tropical and developing countries there are few cases reported in AIDS patients. Most patients with disseminated strongyloidiasis present with fever, cough, diarrhea and shortness of breath. Chest radiographs usually show diffuse infiltrates. The diagnosis has been made by finding the helminth in respiratory secretions or stool. Enteric organisms like Escherichia coli can often be isolated in the blood or cerebrospinal fluid. We report two cases of disseminated strongyloidiasis in AIDS patients, in which stercoralis larvae were detected in sputum and stool samples.


Assuntos
Infecções Oportunistas Relacionadas com a AIDS/diagnóstico , Strongyloides stercoralis/isolamento & purificação , Estrongiloidíase/diagnóstico , Infecções Oportunistas Relacionadas com a AIDS/parasitologia , Adulto , Animais , Fezes/parasitologia , Humanos , Masculino , Escarro/parasitologia
7.
Acta gastroenterol. latinoam ; 31(5): 399-402, 2001. ilus
Artigo em Espanhol | LILACS | ID: lil-301648

RESUMO

El Strongyloides stercoralis es un nematelminto de distribución universal, que en pacientes con alteraciones de la respuesta inmune celular, puede provocar infecciones diseminadas graves. Las formas extraintestinales de la estrongiloidosis han sido publicadas con poca frecuencia, a pesar de la elevada prevalencia de infección por este parásito en áreas de clima tropical y en países en vías de desarrollo. Existen escasas publicaciones en pacientes con SIDA. La mayoría de los casos presentan compromiso gastrointestinal, respiratorio, cutáneo y del SNC. La radiografía de tóraz revela la existencia de infiltrados intersticiales difusos. El diagnóstico se confirma por el hallazgo de las larvas rhabditoides en las materias fecales o en el esputo e incluso en el LCR. Con frecuencia, las infecciones diseminadas por este helminto se asocian con septicemias o meningitis causadas por bacilos gram negativos, especialmente Escherichia coli. Presentamos 2 casos de estrongiloidosis diseminada en pacientes con SIDA con hallazgo de larvas en materias fecales y esputo.


Assuntos
Animais , Humanos , Masculino , Adulto , Infecções Oportunistas Relacionadas com a AIDS , Strongyloides stercoralis , Estrongiloidíase , Infecções Oportunistas Relacionadas com a AIDS , Fezes , Escarro
8.
Acta gastroenterol. latinoam ; 31(5): 399-402, 2001.
Artigo em Espanhol | BINACIS | ID: bin-39326

RESUMO

Strongyloides stercoralis is an intestinal nematode that infects humans worldwide. Infected patients with severe involvement of cellular immunity may develop a syndrome characterized by the dissemination of larvae throughout the body. Extraintestinal strongyloidiasis has been infrequently reported and despite the prevalence of the helminth in tropical and developing countries there are few cases reported in AIDS patients. Most patients with disseminated strongyloidiasis present with fever, cough, diarrhea and shortness of breath. Chest radiographs usually show diffuse infiltrates. The diagnosis has been made by finding the helminth in respiratory secretions or stool. Enteric organisms like Escherichia coli can often be isolated in the blood or cerebrospinal fluid. We report two cases of disseminated strongyloidiasis in AIDS patients, in which stercoralis larvae were detected in sputum and stool samples.

9.
Acta gastroenterol. latinoam ; 31(5): 399-402, 2001. ilus
Artigo em Espanhol | BINACIS | ID: bin-9153

RESUMO

El Strongyloides stercoralis es un nematelminto de distribución universal, que en pacientes con alteraciones de la respuesta inmune celular, puede provocar infecciones diseminadas graves. Las formas extraintestinales de la estrongiloidosis han sido publicadas con poca frecuencia, a pesar de la elevada prevalencia de infección por este parásito en áreas de clima tropical y en países en vías de desarrollo. Existen escasas publicaciones en pacientes con SIDA. La mayoría de los casos presentan compromiso gastrointestinal, respiratorio, cutáneo y del SNC. La radiografía de tóraz revela la existencia de infiltrados intersticiales difusos. El diagnóstico se confirma por el hallazgo de las larvas rhabditoides en las materias fecales o en el esputo e incluso en el LCR. Con frecuencia, las infecciones diseminadas por este helminto se asocian con septicemias o meningitis causadas por bacilos gram negativos, especialmente Escherichia coli. Presentamos 2 casos de estrongiloidosis diseminada en pacientes con SIDA con hallazgo de larvas en materias fecales y esputo. (Au)


Assuntos
Animais , Humanos , Masculino , Adulto , Strongyloides stercoralis/isolamento & purificação , Estrongiloidíase/diagnóstico , Infecções Oportunistas Relacionadas com a AIDS/diagnóstico , Fezes/parasitologia , Escarro/parasitologia , Infecções Oportunistas Relacionadas com a AIDS/parasitologia
10.
J Invasive Cardiol ; 11(11): 685-7, 1999 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-10745464

RESUMO

The single coronary artery is an uncommon congenital defect. We report on a patient admitted to our hospital with an acute myocardial infarction and a single coronary artery arising from the left sinus of Valsalva who was treated with coronary angioplasty and stent implantation. We have not found an identical report of stenting in such an anomaly in the medical literature.


Assuntos
Implante de Prótese Vascular , Anomalias dos Vasos Coronários/terapia , Infarto do Miocárdio/terapia , Stents , Adulto , Angioplastia Coronária com Balão , Anomalias dos Vasos Coronários/complicações , Humanos , Masculino , Infarto do Miocárdio/complicações
11.
Spinal Cord ; 36(5): 349-52, 1998 May.
Artigo em Inglês | MEDLINE | ID: mdl-9601116

RESUMO

The aim of this paper is to review the incidence and characteristics found in traumatic spinal cord injury (SCI) occurring in patients with long-standing ankylosing spondylitis (AS). The incidence of patients with traumatic SCI admitted to our unit from January 1984 to February 1996 was 2% (15 out of 893). They were all men with a mean age of 56 years. Most frequently the etiology of the lesion was a motor vehicle accident and the injury was mainly due to a hyperextension mechanism. Acute spinal fracture occurred in 13 patients, all involving the cervical region. No fracture was observed in two patients with thoracic neurological level. Three patients presented with an interval free period of neurological symptoms in whom a spinal epidural hematoma was visualized with magnetic resonance imaging. On admission eight patients were diagnosed as having complete SCI and the other seven an incomplete SCI. In the acute phase, respiratory complications were most frequent, causing six patients to die. Treatment was conservative in 14 patients. Multidisciplinary management of these patients should be implemented in an institution equipped with both a Spinal Injury Unit and an Intensive Care Unit.


Assuntos
Traumatismos da Medula Espinal/complicações , Espondilite Anquilosante/complicações , Adulto , Idoso , Idoso de 80 Anos ou mais , Avaliação da Deficiência , Humanos , Incidência , Masculino , Pessoa de Meia-Idade , Mortalidade , Pescoço , Traumatismos da Medula Espinal/epidemiologia , Traumatismos da Medula Espinal/terapia , Tórax
12.
Spinal Cord ; 35(10): 664-73, 1997 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-9347595

RESUMO

The aim of this study was to correlate traumatic spinal cord injury (SCI) patient's outcome with magnetic resonance imaging (MRI) performed within the first 15 days following trauma. We retrospectively analyzed 55 SCI patients. Upon admission, 28 were diagnosed as having a complete SCI (51%), versus 27 with an incomplete SCI (49%). All of the patients with a normal pattern on MRI (four cases), had an incomplete SCI, whereas all patients (15 cases) presenting with a hemorrhage pattern (Type 1) had a complete SCI (P = 0.0001). Fourteen of the 15 individuals (93.4%) with the edema pattern (Type II) had an incomplete SCI (P = 0.001), while the other patient had neurological deterioration, and a syrinx was noted 2 years later (6.6%). Among the 10 individuals showing a contusion pattern (Type III), seven were admitted with an incomplete SCI (70%) and three with a complete SCI (30%). The compression pattern tends to be associated with a complete SCI in 77.8% (seven of nine patients). All patients with a transection pattern on MRI (two cases) were clinically diagnosed as having a complete SCI. Early functional prognosis may be established on the basis of clinical presentation of SCI and associated MRI. Cord hemorrhage and transection are irreversible, while edema has a potential for neurological recovery. Cord contusion tends to be associated with an incomplete SCI, unlike the compression pattern, in which the prognosis depends on the degree of the initial neurological damage.


Assuntos
Imageamento por Ressonância Magnética , Traumatismos da Medula Espinal/diagnóstico , Adolescente , Adulto , Idoso , Distribuição de Qui-Quadrado , Diagnóstico Diferencial , Feminino , Humanos , Escala de Gravidade do Ferimento , Masculino , Pessoa de Meia-Idade , Prognóstico , Estudos Retrospectivos , Sensibilidade e Especificidade , Compressão da Medula Espinal/diagnóstico , Compressão da Medula Espinal/fisiopatologia , Traumatismos da Medula Espinal/fisiopatologia
13.
Spinal Cord ; 34(10): 592-3, 1996 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-8896124

RESUMO

The effect of ascorbic acid on urine pH was studied in spinal cord injury patients. Their urine was not colonized by urease positive microorganisms. The study was designed to compare the baseline urine pH value and the urine pH value after the administration of placebo or ascorbic acid 500 mg/6 h. The diet and medical treatment were not controlled. A significant decrease in urine pH value was not obtained. There was no clinical benefit from the use of ascorbic acid.


Assuntos
Ácido Ascórbico/uso terapêutico , Traumatismos da Medula Espinal/complicações , Infecções Urinárias/complicações , Infecções Urinárias/prevenção & controle , Adolescente , Adulto , Ácido Ascórbico/urina , Dieta , Feminino , Humanos , Concentração de Íons de Hidrogênio , Masculino , Pessoa de Meia-Idade , Método Simples-Cego , Urease/urina , Bexiga Urinaria Neurogênica/microbiologia , Infecções Urinárias/microbiologia
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